State-owned Myanmar National Airlines will start using the new arrival and departure lounge for overseas flights on Sunday, according to Yangon Aerodrome.
The airline flies to Bangkok, Singapore and Hong Kong in addition to domestic cities.
The reinforced concrete and steel building is 240 metres long and 98 metres high. It has five-storeys and a 100-metre sky link to the car park.
Arrivals and departures are in the basement, passport control is on the first floor and security checks and departure gates are on the first floor. Shops are on the second floor and there is a recreation area on the third floor.
According to the airport development plan, Yangon Aerodrome will upgrade the airport to serve six million passengers annually. The airport currently handles 2.7 million.
The company is replacing the domestic terminal. It has already constructed car parks and roads within the airport.